Mathematical modeling of HIV-1 infection and drug therapy

DOI10.1007/978-3-540-76784-8_3MaRDI QIDQ4607136zbMATH OpenOpenAlexFDO

Authors Libin Rong, Zhilan Feng, Alan S. Perelson

Publication date 12 March 2018

Published in Applied Optimization (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-540-76784-8_3

zbMATH Keywords

antiretroviral therapydrug resistancevirus dynamicsviral equilibriumhuman immunodeficiencyviral load decays

Mathematics Subject Classification ID

Medical applications (general) (92C50) Medical epidemiology (92C60) Epidemiology (92D30)

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Cites work

• scientific article; zbMATH DE number 3701499 (Why is no real title available?)
• scientific article; zbMATH DE number 1974540 (Why is no real title available?)
• scientific article; zbMATH DE number 2038872 (Why is no real title available?)
• A Two-Strain Tuberculosis Model with Age of Infection
• A model for treatment strategy in the chemotherapy of AIDS
• A model of HIV-1 pathogenesis that includes an intracellular delay
• A two-strain HIV-1 mathematical model to assess the effects of chemotherapy on disease parameters
• An age-structured model of HIV infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells
• Comparison of three kinetic models of HIV-1 infection: implications for optimization of treatment
• Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
• Dissociation of HIV-1 from follicular dendritic cells during HAART: Mathematical analysis
• Drug concentration heterogeneity facilitates the evolution of drug resistance
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• Emergence of HIV-1 drug resistance during antiretroviral treatment
• Estimating kinetic parameters from HIV primary infection data through the eyes of three different mathematical models
• Human Immunodeficiency Virus: Quasi-Species and Drug Resistance
• Influence of delayed viral production on viral dynamics in HIV-1 infected patients
• Mathematical Analysis of Age‐Structured HIV‐1 Dynamics with Combination Antiretroviral Therapy
• Mathematical Analysis of HIV-1 Dynamics in Vivo
• Mathematical analysis of delay differential equation models of HIV-1 infection
• Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity
• Optimizing within-host viral fitness: infected cell lifespan and virion production rate
• Predicting differential responses to structured treatment interruptions during HAART
• Production of resistant HIV mutants during antiretroviral therapy
• The influence of anti-viral drug therapy on the evolution of HIV-1 pathogens
• Understanding drug resistance for monotherapy treatment of HIV infection

Cited in

(26)

• Vibrational Markovian modelling of footprints after the interaction of antibiotics with the packaging region of HIV type 1
• A CTL-INCLUSIVE MATHEMATICAL MODEL FOR ANTIRETROVIRAL TREATMENT OF HIV INFECTION
• The effects of latent infection on the dynamics of HIV
• scientific article; zbMATH DE number 6840954 (Why is no real title available?)
• MODELING THE DRUG THERAPY FOR HIV INFECTION
• Determination of number of infected cells and concentration of viral particles in plasma during HIV-1 infections using Shehu transformation
• Examining HIV progression mechanisms via mathematical approaches
• Effects of combined drug therapy on HIV-1 infection dynamics
• Periodic oscillations in HIV transmission model with intracellular time delay and infection-age structure
• HIV infection dynamics and viral rebound: modeling results from humanized mice
• Mathematical modeling and dynamics of HIV progression and treatment
• A viral load-based cellular automata approach to modeling HIV dynamics and drug treatment
• Mathematical modeling of viral kinetics under immune control during primary HIV-1 infection
• A mathematical model for treatment-resistant mutations of HIV
• A multi-scale mathematical modeling framework to investigate anti-viral therapeutic opportunities in targeting HIV-1 accessory proteins
• Modeling within-host viral dynamics: the role of CTL immune responses in the evolution of drug resistance
• Mathematical modelling of internal HIV dynamics
• On the intra-host dynamics of HIV-1 infections
• Modelling the immunopathogenesis of HIV-1 infection and the effect of multidrug therapy: the role of fusion inhibitors in HAART
• Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents
• Within-host dynamics and treatment of HIV-1 infection: unanswered questions and challenges for computational biologists
• Mathematical models for therapeutic approaches to control HIV disease transmission
• Dynamical model of in-host HIV infection: with drug therapy and multi viral strains
• scientific article; zbMATH DE number 2038872 (Why is no real title available?)
• The influence of anti-viral drug therapy on the evolution of HIV-1 pathogens
• A two-strain HIV-1 mathematical model to assess the effects of chemotherapy on disease parameters

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