A group sequential test for treatment effect based on the Fine-Gray model

DOI10.1111/BIOM.12871zbMATH Open1414.62460OpenAlexW2793585079WikidataQ52726861 ScholiaQ52726861MaRDI QIDQ4628366FDOQ4628366

Authors: Michael J. Martens, Brent R. Logan 

Publication date: 13 March 2019

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc6146968

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zbMATH Keywords

group sequential designgraft versus host diseasehematopoietic cell transplantationcompeting risks analysisFine-Gray regression model

Mathematics Subject Classification ID

General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10)

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• Sequential trials in the context of competing risks: concepts and case study, with R and SAS code
• A unified approach to sample size and power determination for testing parameters in generalized linear and time-to-event regression models
• Group sequential tests for treatment effect on survival and cumulative incidence at a fixed time point

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