Accounting for Variability in the Use of Permutation Testing to Detect Quantitative Trait Loci

DOI10.1111/J.0006-341X.2000.00052.XMaRDI QIDQ4668372zbMATH OpenOpenAlexWikidataFDO

Authors Dan Nettleton, Rebecca W. Doerge

Publication date 19 April 2005

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.0006-341x.2000.00052.x

zbMATH Keywords

permutation testMonte Carlo methods\(p\)-valuestatistical geneticsQTL mappingnumber of permutations

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05) Genetics and epigenetics (92D10) Testing in survival analysis and censored data (62N03)

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(5)

• On the power to detect SNP/phenotype association in candidate quantitative trait loci genomic regions: a simulation study
• scientific article; zbMATH DE number 819344 (Why is no real title available?)
• Estimation of false discovery rate using sequential permutation \(p\)-values
• Using Alpha Wisely: Improving Power to Detect Multiple QTL
• A geometric interpretation of the permutation \(p\)-value and its application in eQTL studies

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