Inferring the Location and Effect of Tumor Suppressor Genes by Instability‐Selection Modeling of Allelic‐Loss Data

DOI10.1111/j.0006-341X.2000.01088.xzbMath1060.62646WikidataQ30621296 ScholiaQ30621296MaRDI QIDQ4670462

Yoonjung Lee, Michael A. Newton

Publication date: 22 April 2005

Published in: Biometrics (Search for Journal in Brave)

zbMATH Keywords

correlated binary dataloss of heterozygosityallelic imbalancecancer gene mappingchromosomal deletionslogarithm of odds scoreMarkovian deletion process

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Estimation in survival analysis and censored data (62N02) Testing in survival analysis and censored data (62N03)

Related Items (2)

Inferring the Location of Tumor Suppressor Genes by Modeling Frequency of Allelic Loss ⋮ A Semiparametric Bayesian Model for Repeatedly Repeated Binary Outcomes

Cites Work

• Probability approximations via the Poisson clumping heuristic
• The problem of regions
• Markov chains for exploring posterior distributions. (With discussion)
• Markov processes for modeling and analyzing a new genetic mapping method
• Bayes Factors
• The Weighted Likelihood Ratio, Linear Hypotheses on Normal Location Parameters
• Statistical methods for DNA sequence segmentation

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