SYSTEMIC LUPUS ERYTHEMATOSUS IN AFRICAN-AMERICAN WOMEN: COGNITIVE PHYSIOLOGICAL MODULES, AUTOIMMUNE DISEASE, AND STRUCTURED PSYCHOSOCIAL STRESS

DOI10.1142/S0219525903001092zbMATH Open1100.91575arXivq-bio/0311028OpenAlexW2085942369MaRDI QIDQ4670841FDOQ4670841

Authors: Rodrick Wallace 

Publication date: 22 April 2005

Published in: Advances in Complex Systems (Search for Journal in Brave)

Abstract: Examining elevated rates of systemic lupus erythematosus in African-American women from perspectives of immune cognition suggests the disease constitutes an internalized physiological image of external structured psychosocial stress, a 'pathogenic social hierarchy' involving the synergism of racism and gender discrimination in the context of policy-driven social disintegration which has particularly affected ethnic minorities in the USA. The disorder represents the punctuated resetting of normal immune self-image to a self-attacking excited state, a process formally analogous to models of punctuated equilibrium in evolutionary theory. Both onset and progression of disease may be stratified by a relation to cyclic physiological responses which are long in comparison with heartbeat period: circadian, hormonal, and annual light/termperature cycles.

Full work available at URL: https://arxiv.org/abs/q-bio/0311028

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zbMATH Keywords

information theorylupusracismcircadianAfrican-Americanpsychosocial stress

Mathematics Subject Classification ID

Cognitive psychology (91E10)

Cites Work

• Renormalization group and critical phenomena. I: Renormalization group and the Kadanoff scaling picture
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• Toward Cultural Oncology: The Evolutionary Information Dynamics of Cancer
• Immune Cognition and Vaccine Strategy: Pathogenic Challenge and Ecological Resilience

Cited In (2)

• Toward Cultural Oncology: The Evolutionary Information Dynamics of Cancer
• STRUCTURED PSYCHOSOCIAL STRESS AND THERAPEUTIC FAILURE

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