Approximate Likelihood Methods for Estimating Local Recombination Rates

DOI10.1111/1467-9868.00355MaRDI QIDQ4672152zbMATH OpenOpenAlexFDO

Authors Paul Fearnhead, Peter Donnelly

Publication date 29 April 2005

Published in Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/1467-9868.00355

zbMATH Keywords

CoalescentComposite likelihoodMarginal likelihoodPseudolikelihoodLipoprotein lipaseMutation rate heterogeneityRecombination rateRecombinational hot spot

Mathematics Subject Classification ID

Point estimation (62F10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

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Cites work

• The coalescent

Cited in

(13)

• ML, PL, QL in Markov Chain Models
• scientific article; zbMATH DE number 7008406 (Why is no real title available?)
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• On full efficiency of the maximum composite likelihood estimator
• scientific article; zbMATH DE number 5221540 (Why is no real title available?)
• A composite-conditional-likelihood approach for gene mapping based on linkage disequilibrium in windows of marker loci
• Consistency of estimators of the population-scaled recombination rate
• Estimating the relative rate of recombination to mutation in bacteria from single-locus variants using composite likelihood methods
• An approximate likelihood for genetic data under a model with recombination and population splitting
• On composite marginal likelihoods
• An estimator for the recombination rate from a continuously observed diffusion of haplotype frequencies
• Composite likelihood ratio testing under nonstandard conditions using tangent cones
• Composite likelihood-based inferences on genetic data from dependent loci

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