A mathematical model of the human metabolic system and metabolic flexibility

DOI10.1007/S11538-014-0001-4MaRDI QIDQ467749zbMATH OpenOpenAlexWikidataFDO

Authors Taliesin Pearson, Jonathan A. D. Wattis, J. R. King, Ian A. MacDonald, Dawn J. Mazzatti

Publication date 5 November 2014

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL http://eprints.nottingham.ac.uk/29802/

zbMATH Keywords

glucosemulticompartmental modellinginsulinfree fatty acidstriglyceride

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Physiology (general) (92C30)

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Cites work

• A continuum receptor model of hepatic lipoprotein metabolism
• A dynamical model of lipoprotein metabolism
• An integrated mathematical model of the dynamics of blood glucose and its hormonal control
• Asymptotic properties of a delay differential equation model for the interaction of glucose with plasma and interstitial insulin.
• Dynamics of starvation in humans
• Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes
• Mathematical modelling of competitive LDL/VLDL binding and uptake by hepatocytes
• Mathematical modelling of hepatic lipid metabolism
• Mathematical modelling of the intravenous glucose tolerance test
• Modeling the glucose-insulin regulatory system and ultradian insulin secretory oscillations with two explicit time delays
• Numerical bifurcation analysis of delay differential equations arising from physiological modeling

Cited in

(8)

• Mathematical model for the administration of the oxytocin therapy of inflammatory diseases in healthy men
• A minimal model for hepatic fatty acid balance during fasting: application to PPAR alpha-deficient mice
• A systemic approach to explore the flexibility of energy stores at the cellular scale: examples from muscle cells
• The effects of insulin resistance on individual tissues: an application of a mathematical model of metabolism in humans
• Mathematical model of diabetes and lipid metabolism linked to diet, leptin sensitivity, insulin sensitivity and VLDLTG clearance predicts paths to health and type II diabetes
• Mechanistic model of fuel selection in the muscle
• Dynamics of the Budyko energy balance model
• Mathematical modelling of hepatic lipid metabolism

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