Designing one-sided group sequential clinical trials to detect a mixture alternative

DOI10.1080/07474946.2018.1466545MaRDI QIDQ4689948zbMATH OpenOpenAlexWikidataFDO

Authors Hua Peng, Daniel R. Jeske, Weixin Yao, Ashis SenGupta

Publication date 22 October 2018

Published in Sequential Analysis (Search for Journal in Brave)

Full work available at URL https://escholarship.org/uc/item/7qx0d0xr

zbMATH Keywords

error spending approachgroup sequential designmixture modelpowersample sizetreatment effect

Mathematics Subject Classification ID

Point estimation (62F10) Hypothesis testing in multivariate analysis (62H15) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Sequential statistical design (62L05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cites work

• \(P^{3}\) approach to intersection-union testing of hypotheses
• A review of optimality of multivariate tests
• Approximately Optimal One-Parameter Boundaries for Group Sequential Trials
• Bias reduction via resampling for estimation following sequential tests
• Discrete Sequential Boundaries for Clinical Trials
• Group sequential designs using both type I and type II error probability spending functions
• Group Sequential Methods and Software Applications
• scientific article; zbMATH DE number 48701 (Why is no real title available?)
• Most Powerful Tests for Some Non-Exponential Families
• Optimal tests for the correlation coefficient in a symmetric multivariate normal population

Cited in

(2)

• Comparison of dichotomized and distributional approaches in rare event clinical trial design: a fixed Bayesian design
• Sample size calculations for mixture alternatives in a control group vs. treatment group design

Describes a project that uses

Uses Software

• SAS
• EaSt
• SAS/STAT

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