The meaning of sensitivity functions in signaling pathways analysis

DOI10.3934/DCDSB.2014.19.2697MaRDI QIDQ478760zbMATH OpenOpenAlexFDO

Authors Jaroslaw Smieja

Publication date 4 December 2014

Published in Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3934/dcdsb.2014.19.2697

zbMATH Keywords

sensitivity analysisFano factorfrequency-domain analysisparameter rankingsignaling pathways

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Sensitivity (robustness) (93B35) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• Sensitivity analysis of signaling pathway models based on discrete-time measurements
• Toward Modelling and Analysis of Transient and Sustained Behaviour of Signalling Pathways
• Approximations and their consequences for dynamic modelling of signal transduction pathways
• Model based analysis of signaling pathways
• Direct response analysis in cellular signalling networks
• Parameter sensitivity analysis for biochemical reaction networks
• A mathematical approach to the study of signal transduction pathways in MAPK cascade
• Integration of sensitivity and bifurcation analysis to detect critical processes in a model combining signalling and cell population dynamics
• Sensitivity of signaling pathway dynamics to plasmid transfection and its consequences

Cites work

• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• Control theory and systems biology.

Cited in

(3)

• Multisite Mechanisms for Ultrasensitivity in Signal Transduction
• Sensitivity of signaling pathway dynamics to plasmid transfection and its consequences
• Sensitivity analysis of signaling pathway models based on discrete-time measurements

This page was built for publication: The meaning of sensitivity functions in signaling pathways analysis

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q478760)