scientific article; zbMATH DE number 1916651

MaRDI QIDQ4807809zbMATH OpenFDO

Authors Joanna Floros, Momiao Xiong, Ruzong Fan

Publication date 24 July 2003

zbMATH Keywords

powersample sizelinkage disequilibriumallele transmission probabilitiesgenomewide screeningrespiratory distress syndromeTDT statistics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

Recommendations

• Transmission disequilibrium test (TDT) for a pair of linked marker loci
• Sample sizes for the transmission disequilibrium tests: tdt, s-tdt and 1-tdt
• On the combination of transmission/disequilibrium test and mean test for linkage detection using affected sib pairs
• Estimation of linkage and association from allele transmission data
• Screening method for genetic linkage analysis: case of the transmission disequilibrium test

Cited in

(6)

• Transmission disequilibrium test power and sample size in the presence of locus heterogeneity
• Linkage and association studies of QTL for nuclear families by mixed models
• Sequential genotyping within TDT families
• Estimation of linkage and association from allele transmission data
• Transmission disequilibrium test (TDT) for a pair of linked marker loci
• The transmission disequilibrium/heterogeneity test with parental-genotype reconstruction for refined genetic mapping of complex diseases

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