Ultrametric random walk and dynamics of protein molecules
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The authors study the \(p\)-adic equations of an ultrametric random walk and its application to conformational dynamics of protein molecules. Two main experiments are proposed to determine the properties of mobility of protein molecules at temperatures from 300 to 4 K: the kinetics of CO binding to myoglobin and the spectral diffusion in proteins. It is found that the \(p\)-adic random walk allows to build a unified picture of the conformational mobility of protein molecules at low temperatures and that the mobility varies in a self-similar way.
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- Understanding bistability in complex enzyme-driven reaction networks
Cited in
(27)- Ultrametricity of fluctuation dynamic mobility of protein molecules
- Model of \(p\)-adic random walk in a potential
- Transience and recurrence of random walks on percolation clusters in an ultrametric space
- Ultrametric diffusion, rugged energy landscapes and transition networks
- Analysis of a one-dimensional random walk with irreversible losses at each step: applications for protein movement on DNA
- New bases in the space of square integrable functions on the field of \(p\)-adic numbers and their applications
- \(p\)-adic mathematical physics: the first 30 years
- Complete systems of eigenfunctions of the Vladimirov operator in \(L^2(B_r)\) and \(L^2(\mathbb{Q}_p)\)
- Methods and applications of ultrametric and \(p\)-adic analysis: from wavelet theory to biophysics
- Ultrametricity in the theory of complex systems
- Ultrametric theory of conformational dynamics of protein molecules in a functional state and the description of experiments on the kinetics of CO binding to myoglobin
- \(p\)-adic models for ultrametric diffusion in conformational dynamics of macromolecules
- Ultrametric diffusion in a strong centrally symmetric field
- Application of \(p\)-adic analysis methods in describing Markov processes on ultrametric spaces isometrically embedded into \(\mathbb{Q}_p\)
- Random systems in ultrametric spaces
- Mathematical modeling of molecular ``nano-machines
- Hierarchical model of the actomyosin molecular motor based on ultrametric diffusion with drift
- Oscillations in \(p\)-adic diffusion processes and simulation of the conformational dynamics of protein
- p-adic Brownian motion is a scaling limit
- Power laws and logarithmic oscillations in diffusion processes on discrete ultrametric spaces
- Brownian motion in the p-adic integers is a limit of discrete time random walks
- A nonautonomous p-adic diffusion equation on time changing graphs
- Functional calculus and semilinear evolution equations for the Taibleson operator on non-Archimedean local fields
- Classical first passage problems for p-adic stochastic processes
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- Hörmander classes of pseudo-differential operators over the compact group of \(p\)-adic integers
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