Information and information fractions for design and sequential monitoring of clinical trials

DOI10.1080/03610929408831263zbMath0825.62095OpenAlexW2070581312MaRDI QIDQ4843737

K. K. Gordon Lan, David L. Demets, David M. Reboussin

Publication date: 17 August 1995

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610929408831263

zbMATH Keywords

repeated measuressurvival analysisspending functiongroup sequential boundsLan-DeMets method

Mathematics Subject Classification ID

Statistics (62-XX)

Related Items (5)

An Efficient Allocation in Group Sequential Tests for the Linear Mixed Effects Model ⋮ An overview of group sequential methods in longitudinal clinical trials ⋮ Testing Secondary Hypotheses Following Sequential Clinical Trials ⋮ Basic concepts of group sequential and adaptive group sequential test procedures ⋮ Point estimation after early stopping in a repeated measures trial

Cites Work

• Random-Effects Models for Longitudinal Data
• Sequential analysis of the proportional hazards model
• Discrete Sequential Boundaries for Clinical Trials
• Evaluation of Sample Size and Power for Analyses of Survival with Allowance for Nonuniform Patient Entry, Losses to Follow-Up, Noncompliance, and Stratification
• The asymptotic joint distribution of the efficient scores test for the proportional hazards model calculated over time
• Sequential Clinical Trials for Normal Variates Using Interval Composite Hypotheses
• Sequential Monitoring for Comparison of Changes in a Response Variable in Clinical Studies

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