Testing for gene-environment and gene-gene interactions under monotonicity constraints
DOI10.1080/01621459.2012.726892zbMATH Open1259.62098OpenAlexW2104709631MaRDI QIDQ4904722FDOQ4904722
Authors: Summer S. Han, Philip S. Rosenberg, Nilanjan Chatterjee 
Publication date: 31 January 2013
Published in: Journal of the American Statistical Association (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1080/01621459.2012.726892
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isotonic regressionorder restrictionsgene-environment interactionsgenome-wide association study (GWAS)constrained likelihood ratio test
Parametric hypothesis testing (62F03) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Parametric inference under constraints (62F30)
Cites Work
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- Logistic disease incidence models and case-control studies
- An algorithm for isotonic regression for two or more independent variables
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- A TEST OF HOMOGENEITY FOR ORDERED ALTERNATIVES
- A TEST OF HOMOGENEITY FOR ORDERED ALTERNATIVES. II
- Semiparametric maximum likelihood estimation exploiting gene-environment independence in case-control studies
- An algorithm for monotone regression with one or more independent variables
Cited In (10)
- A unified set-based test with adaptive filtering for gene-environment interaction analyses
- Algebraic methods for studying interactions between epidemiological variables
- AGGrEGATOr: A Gene-based GEne-Gene interActTiOn test for case-control association studies
- Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines
- An exposure-weighted score test for genetic associations integrating environmental risk factors
- Testing for gene-gene interaction in case-control GWAS
- Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction
- Testing for gene-environment interaction under exposure misspecification
- Detecting rare and common haplotype-environment interaction under uncertainty of gene-environment independence assumption
- Detecting two-locus gene-gene effects using monotonisation of the penetrance matrix
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