Evaluation of statistical methods for analysis of small-sample longitudinal clinical trials with dropouts

DOI10.5183/JJSCS1988.20.1MaRDI QIDQ4916872zbMATH OpenOpenAlexFDO

Authors Takayuki Abe, Manabu Iwasaki

Publication date 26 April 2013

Published in Journal of the Japanese Society of Computational Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.5183/jjscs1988.20.1

zbMATH Keywords

Bayesian least squaresmissing datamultiple imputationpredictive mean matching

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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(8)

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• Last observation analysis in ANOVA and ANCOVA
• Application of multiple imputation in analysis of data from clinical trials with treatment related dropouts
• A comparison of the random-effects pattern mixture model with last-observation-carried-forward(locf) analysis in longitudinal clinical trials with dropouts
• MULTIPLE IMPUTATION COMPARED WITH SOME INFORMATIVE DROPOUT PROCEDURES IN THE ESTIMATION AND COMPARISON OF RATES OF CHANGE IN LONGITUDINAL CLINICAL TRIALS WITH DROPOUTS
• A simple correction to completer analyses and improvement on baseline observation carried forward
• Longitudinal and incomplete clinical studies
• Simulation to evaluate the treatment of missing data in longitudinal settings in the context of clinical trials

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