Multiplicity considerations for subgroup analysis subject to consistency constraint

DOI10.1002/BIMJ.201200065zbMATH Open1441.62274OpenAlexW2112863332WikidataQ86592808 ScholiaQ86592808MaRDI QIDQ4921959FDOQ4921959

Mohammad Huque, Mohamed Alosh

Publication date: 28 May 2013

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201200065

Recommendations

• Protocol Designed Subgroup Analyses in Multiarmed Clinical Trials: Multiplicity Aspects
• A multiple comparison procedure for dose-finding trials with subpopulations
• Adaptive designs for subpopulation analysis optimizing utility functions
• Treatment effect heterogeneity for univariate subgroups in clinical trials: shrinkage, standardization, or else
• Subgroup inference for multiple treatments and multiple endpoints in an Alzheimer's disease treatment trial

zbMATH Keywords

subgroup analysisconsistency ensured multiplicity methodstargeted subgrouptreatment-by-subgroup interaction

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• A flexible fixed-sequence testing method for hierarchically ordered correlated multiple endpoints in clinical trials
• Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests

Cited In (2)

• Protocol Designed Subgroup Analyses in Multiarmed Clinical Trials: Multiplicity Aspects
• The threshold for subgroup profiles to agree is $\Omega(\log n)$

This page was built for publication: Multiplicity considerations for subgroup analysis subject to consistency constraint

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q4921959)