Time-stepping techniques to enable the simulation of bursting behavior in a physiologically realistic computational islet

DOI10.1016/j.mbs.2015.02.001zbMath1345.92048OpenAlexW2055747566WikidataQ50751300 ScholiaQ50751300MaRDI QIDQ494446

Bradford E. Peercy, Samuel Khuvis, Matthias K. Gobbert

Publication date: 1 September 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2015.02.001

zbMATH Keywords

stiff ordinary differential equationsautomatic differentiationnumerical differentiation formulasbeta cellscomputational islet

Mathematics Subject Classification ID

Symbolic computation and algebraic computation (68W30) Physiology (general) (92C30) Computational methods for problems pertaining to biology (92-08) Numerical methods for stiff equations (65L04) Biological rhythms and synchronization (92B25)

Uses Software

• Matlab
• ode23
• ADiMat
• ode45
• Ode15s
• ode113
• ode23s
• MATLAB ODE suite

Cites Work

• A calcium-based phantom bursting model for pancreatic islets
• Diffusively coupled bursters: Effects of cell heterogeneity
• The MATLAB ODE Suite

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