Roman and Vatican crossover designs

MaRDI QIDQ4959475zbMATH OpenFDO

Authors M. A. Ollis

Publication date 13 September 2021

Full work available at URL https://arxiv.org/abs/1911.12403, http://www.the-ica.org/Volumes/92/Reprints/BICA2020-33-Reprint.pdf

zbMATH Keywords

crossover designLatin squarerow-complete Latin squareterraceVatican square

Mathematics Subject Classification ID

Orthogonal arrays, Latin squares, Room squares (05B15) Other designs, configurations (05B30) Arithmetic and combinatorial problems involving abstract finite groups (20D60) Design of statistical experiments (62K99)

Abstract: Latin squares with a balance property among adjacent pairs of symbols---being "Roman" or "row-complete"---have long been used as uniform crossover designs with the number of treatments, periods and subjects all equal. This has been generalized in two ways: to crossover designs with more subjects and to balance properties at greater distances. We consider both of these simultaneously, introducing and constructing {em Vatican designs}: these have $ellt$ subjects, $t$ periods and treatments, and, for each $d$ in the range $1leqd<t$, the number of times that any subject receives treatment $j$ exactly $d$ periods after receiving treatment $i$ is at most $ell$. Results include showing the existence of Vatican designs when $t+1$ is prime (for any $ell$), when $5leqtleq14$ and $ell>1$, and when $tin3,15$ and $ell$ is even.

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