Functional optimality of the sulcus pattern of the human brain

DOI10.1093/IMAMMB/DQY007zbMATH Open1418.92007arXiv1801.05703OpenAlexW2963439344WikidataQ88916831 ScholiaQ88916831MaRDI QIDQ4968271FDOQ4968271

Authors: S. Heyden, M. Ortiz 

Publication date: 12 July 2019

Published in: Mathematical Medicine and Biology: A Journal of the IMA (Search for Journal in Brave)

Abstract: We develop a mathematical model of information transmission across the biological neural network of the human brain. The overall function of the brain consists of the emergent processes resulting from the spread of information through the neural network. The capacity of the brain is therefore related to the rate at which it can transmit information through the neural network. The particular transmission model under consideration allows for information to be transmitted along multiple paths between points of the cortex. The resulting transmission rates are governed by potential theory. According to this theory, the brain has preferred and quantized transmission modes that correspond to eigenfunctions of the classical Steklov eigenvalue problem, with the reciprocal eigenvalues quantifying the corresponding transmission rates. We take the model as a basis for testing the hypothesis that the sulcus pattern of the human brain has evolved to maximize the rate of transmission of information between points in the cerebral cortex. We show that the introduction of sulci, or cuts, in an otherwise smooth domain indeed increases the overall transmission rate. We demonstrate this result by means of numerical experiments concerned with a spherical domain with a varying number of slits on its surface.

Full work available at URL: https://arxiv.org/abs/1801.05703

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zbMATH Keywords

neural networksSteklov spectrumbrain gyrification

Mathematics Subject Classification ID

Neural biology (92C20) Neural networks for/in biological studies, artificial life and related topics (92B20)

Cited In (3)

• Optimizing information transmission rates drives brain gyrification
• Statistical study on cortical sulci of human brains
• On an interior Calderón operator and a related Steklov eigenproblem for Maxwell's equations

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