Construction of confidence regions in the ROC space after the estimation of the optimal Youden index-based cut-off point

DOI10.1111/BIOM.12107zbMATH Open1419.62307OpenAlexW2159193885WikidataQ44490145 ScholiaQ44490145MaRDI QIDQ4979252FDOQ4979252

Authors: Leonidas E. Bantis, Christos T. Nakas, Benjamin Reiser 

Publication date: 17 June 2014

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/biom.12107

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zbMATH Keywords

logsplinesensitivityspecificitydelta methodROC curveYouden index

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric tolerance and confidence regions (62F25) Nonparametric tolerance and confidence regions (62G15)

Cites Work

• Estimation of the diagnostic threshold accounting for decision costs and sampling uncertainty
• Confidence Intervals for the Youden Index and Corresponding Optimal Cut-Point
• A study of logspline density estimation
• A family of nonparametric statistics for comparing diagnostic markers with paired or unpaired data
• Two transformation models for estimating an ROC curve derived from continuous data
• The Large-Sample Behavior of Transformations to Normality
• Asymptotic and qualitative performance of non-parametric density estimators: a comparative study

Cited In (23)

• A new accuracy metric under three classes when subclasses are involved and its confidence interval estimation
• The length of the receiver operating characteristic curve and the two cutoff Youden index within a robust framework for discovery, evaluation, and cutoff estimation in biomarker studies involving improper receiver operating characteristic curves
• Estimation of Youden index and its associated optimal cut-point when the parameters of gama biomarkers are estimated by the method of moments
• Construction of confidence intervals for the maximum of the youden index and the corresponding cutoff point of a continuous biomarker
• Joint inference about sensitivity and specificity at the optimal cut-off point associated with Youden index
• Confidence interval construction for the Youden index based on partially validated series
• Youden index and associated cut-points for three ordinal diagnostic groups
• Exact confidence interval estimation for the Youden index and its corresponding optimal cut-point
• Title not available (Why is that?)
• Confidence Intervals for the Youden Index and Corresponding Optimal Cut-Point
• Estimation of the youden index and its associated cutoff point
• Statistical inference for the difference between two maximized Youden indices obtained from correlated biomarkers
• Construction of joint confidence spaces for the optimal true class fraction triplet in the ROC space using alternative biomarker cutoffs
• A solution for the most basic optimization problem associated with an ROC curve
• Likelihood-type confidence regions for optimal sensitivity and specificity of a diagnostic test
• Joint inference about the AUC and Youden index for paired biomarkers
• Confidence interval estimation for sensitivity and difference between two sensitivities at a given specificity under tree ordering
• Exact inference for disease prevalence based on a test with unknown specificity and sensitivity
• On optimal biomarker cutoffs accounting for misclassification costs in diagnostic trilemmas with applications to pancreatic cancer
• Cutoff estimation and construction of their confidence intervals for continuous biomarkers under ternary umbrella and tree stochastic ordering settings
• Evaluating joint confidence region of hypervolume under ROC manifold and generalized Youden index
• Statistical method of determining a cut off value between normal and disease groups
• Improved nonparametric estimation of the optimal diagnostic cut-off point associated with the Youden index under different sampling schemes

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