Testing SNPs in targeted drug development
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Recommendations
- Confident inference for SNP effects on treatment efficacy
- Discussion on the issue of sample size determination for a targeted to an untargeted and to a mixed effect model-based clinical trial design
- Testing SNPs and sets of SNPs for importance in association studies
- Methods for analysis and visualization of SNP genotype data for complex diseases
- A penalized likelihood approach for investigating gene-drug interactions in pharmacogenetic studies
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