Practical statistical considerations for investigating anti-tumor treatments in mice

DOI10.1080/02664763.2018.1477925MaRDI QIDQ5036504zbMATH OpenOpenAlexWikidataFDO

Authors David Gold, Lixin Lang, Kim Zerba

Publication date 23 February 2022

Published in Journal of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/02664763.2018.1477925

zbMATH Keywords

cancerinferencemousenonlineartumor

Mathematics Subject Classification ID

Applications of statistics (62Pxx)

Recommendations

• Statistical analysis for tumor xenograft experiments in drug development
• Incorporating Historical Control Data When Comparing Tumor Incidence Rates
• Small-sample inference for incomplete longitudinal data with truncation and censoring in tumor xenograft models
• Theoretical investigation of the efficacy of antiangiogenic drugs combined to chemotherapy in xenografted mice
• Computational modeling and experimental investigations to enhance the successful response of anti-PD-1 cancer immunotherapies

Cites work

• Varying Coefficient Model with Unknown Within‐Subject Covariance for Analysis of Tumor Growth Curves

Cited in

(2)

• Efficiency robust score tests for rodent tumourigenicity experiments
• Statistical analysis for tumor xenograft experiments in drug development

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