Germinal center dynamics during acute and chronic infection

DOI10.3934/MBE.2017037zbMATH Open1366.92025OpenAlexW2562000539WikidataQ40370065 ScholiaQ40370065MaRDI QIDQ504659FDOQ504659

Authors: Samantha Erwin, Stanca M. Ciupe 

Publication date: 17 January 2017

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2017037

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zbMATH Keywords

germinal centersB cellssomatic hypermutationsTfh cells

Mathematics Subject Classification ID

Medical applications (general) (92C50) Medical epidemiology (92C60) Developmental biology, pattern formation (92C15)

Cites Work

• A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation
• An analysis of B cell selection mechanisms in germinal centers
• Dynamics of one-pass germinal center models: implications for affinity maturation
• Quantifying T lymphocyte turnover
• Evaluation of multitype mathematical models for CFSE-labeling experiment data
• Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models

Cited In (8)

• Are T cells at the origin of B cell lymphomas?
• The type of seeder cells determines the efficiency of germinal center reactions
• Mathematical modeling of lymphocytes selection in the germinal center
• Exploration of factors affecting the onset and maturation course of follicular lymphoma through simulations of the germinal center
• Dynamics of one-pass germinal center models: implications for affinity maturation
• Dynamics of T cell receptor distributions following acute thymic atrophy and resumption
• The role of geometric features in a germinal center
• A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields

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