Two-stage winner designs for non-inferiority trials with pre-specified non-inferiority margin

DOI10.1016/J.JSPI.2016.10.001zbMATH Open1357.62269OpenAlexW2549595119MaRDI QIDQ505087FDOQ505087

Authors: Pin-Wen Wang, Shou-En Lu, Yong Lin, K. K. Gordon Lan, Weichung Joe Shih 

Publication date: 19 January 2017

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jspi.2016.10.001

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zbMATH Keywords

two-stage designadaptive designnon-inferiority trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential statistical analysis (62L10)

Cites Work

• Adaptive modifications of hypotheses after an interim analysis
• A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
• Normal approximation for two-stage winner design
• Two-stage selection and testing designs for comparative clinical trials
• THE ATTRACTIVENESS OF THE CONCEPT OF A PROSPECTIVELY DESIGNED TWO-STAGE CLINICAL TRIAL
• Drop-the-losers design: normal case

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