Two-stage winner designs for non-inferiority trials with pre-specified non-inferiority margin

DOI10.1016/J.JSPI.2016.10.001MaRDI QIDQ505087zbMATH OpenOpenAlexFDO

Authors Pin-Wen Wang, Shou-En Lu, Yong Lin, K. K. Gordon Lan, Weichung Joe Shih

Publication date 19 January 2017

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jspi.2016.10.001

zbMATH Keywords

two-stage designadaptive designnon-inferiority trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential statistical analysis (62L10)

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Cites work

• A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
• Adaptive modifications of hypotheses after an interim analysis
• Drop-the-losers design: normal case
• Normal approximation for two-stage winner design
• THE ATTRACTIVENESS OF THE CONCEPT OF A PROSPECTIVELY DESIGNED TWO-STAGE CLINICAL TRIAL
• Two-stage selection and testing designs for comparative clinical trials

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