Computational study of the effect of hypoxia on cancer response to radiation treatment

MaRDI QIDQ5065848zbMATH OpenFDO

Authors Topi Korhonen, Jakob H. Lagerlöf, Adrian Muntean

Publication date 22 March 2022

zbMATH Keywords

cancer response to radiationfinite element methodmathematical modeling of hypoxia

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Medical applications (general) (92C50)

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(6)

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• Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia
• Towards the virtual tumor for optimizing radiotherapy treatments of hypoxic tumors: a novel model of heterogeneous tissue vasculature and oxygenation
• A computational study of combination HIFU-chemotherapy as a potential means of overcoming cancer drug resistance
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• Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies

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