Active forces shape the metaphase spindle through a mechanical instability

DOI10.1073/PNAS.2002446117zbMATH Open1485.92040OpenAlexW3037699643WikidataQ96815545 ScholiaQ96815545MaRDI QIDQ5073085FDOQ5073085

Authors: David Oriola, Frank Jülicher, Jan Brugues 

Publication date: 5 May 2022

Published in: Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1073/pnas.2002446117

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Mathematics Subject Classification ID

Liquid crystals (76A15) Cell biology (92C37) Biological fluid mechanics (76Z99)

Cites Work

• Nonlinear Euler buckling

Cited In (3)

• Tug-of-war between opposing molecular motors explains chromosomal oscillation during mitosis
• Mechanical torque promotes bipolarity of the mitotic spindle through multi-centrosomal clustering
• Fingering instability of active nematic droplets

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