Active forces shape the metaphase spindle through a mechanical instability

DOI10.1073/PNAS.2002446117MaRDI QIDQ5073085zbMATH OpenOpenAlexWikidataFDO

Authors David Oriola, Frank Jülicher, Jan Brugues

Publication date 5 May 2022

Published in Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1073/pnas.2002446117

Mathematics Subject Classification ID

Liquid crystals (76A15) Cell biology (92C37) Biological fluid mechanics (76Z99)

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Cites work

• Nonlinear Euler buckling

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(3)

• Tug-of-war between opposing molecular motors explains chromosomal oscillation during mitosis
• Mechanical torque promotes bipolarity of the mitotic spindle through multi-centrosomal clustering
• Fingering instability of active nematic droplets

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