Dynamic Programming for Response-Adaptive Dose-Finding Clinical Trials

DOI10.1287/IJOC.2021.1082MaRDI QIDQ5086016zbMATH OpenOpenAlexFDO

Authors Amir Ali Nasrollahzadeh, Amin Khademi

Publication date 30 June 2022

Published in INFORMS Journal on Computing (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1287/ijoc.2021.1082

zbMATH Keywords

dose-finding studiesadaptive clinical trialsknowledge gradientdynamic learning

Mathematics Subject Classification ID

Operations research, mathematical programming (90-XX)

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Cites work

• scientific article; zbMATH DE number 1984442 (Why is no real title available?)
• A Bayesian Approach to Dose-Response Assessment and Synergy and Its Application to In Vitro Dose-Response Studies
• A Bayesian decision theoretic model of sequential experimentation with delayed response
• A Knowledge-Gradient Policy for Sequential Information Collection
• An Introduction to Optimal Designs for Social and Biomedical Research
• Bayesian forecasting and dynamic models.
• Bayesian learning of dose-response parameters from a cohort under response-guided dosing
• Bayesian look ahead one-stage sampling allocations for selection of the best population
• Consistency of sequential Bayesian sampling policies
• Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule
• DATA AUGMENTATION AND DYNAMIC LINEAR MODELS
• Handbook of methods for designing, monitoring, and analyzing dose-finding trials
• Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges
• Optimal designs for dose-finding studies
• Response-adaptive designs for clinical trials: simultaneous learning from multiple patients
• The knowledge-gradient policy for correlated normal beliefs

Cited in

(3)

• Approximate dynamic programming and its applications to the design of Phase I cancer trials
• Switched systems as models for dynamic clinical trials
• Estimating optimal shared-parameter dynamic regimens with application to a multistage depression clinical trial

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