Optimal, Two-Stage, Adaptive Enrichment Designs for Randomized Trials, using Sparse Linear Programming

DOI10.1111/RSSB.12366MaRDI QIDQ5087154zbMATH OpenOpenAlexFDO

Authors Ethan X. Fang, Han Liu, Michael Rosenblum

Publication date 8 July 2022

Published in Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL https://biostats.bepress.com/cgi/viewcontent.cgi?article=1280&context=jhubiostat

zbMATH Keywords

adaptive enrichment designsdecision rulesmultiple testingoptimization problemssparse linear programs

Mathematics Subject Classification ID

Statistics (62-XX)

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Cited in

(8)

• Inference for a two-stage enrichment design
• Adaptive enrichment designs with a continuous biomarker
• Discussion on “Adaptive enrichment designs with a continuous biomarker” by Nigel Stallard
• Discussion on “Adaptive enrichment designs with a continuous biomarker” by N. Stallard
• Rejoinder to discussion on “Adaptive enrichment designs with a continuous biomarker”
• New insights into adaptive enrichment designs
• Optimal test procedures for multiple hypotheses controlling the familywise expected loss
• Adaptive experiments toward learning treatment effect heterogeneity

Describes a project that uses

Uses Software

• R

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