Parameter selection in dynamic contrast-enhanced magnetic resonance tomography

DOI10.1007/978-3-030-48634-1_6zbMATH Open1452.94019arXiv2002.09129OpenAlexW3040286006MaRDI QIDQ5117955FDOQ5117955

Authors: Kati Niinimäki, Matti Hanhela, Ville Kolehmainen 

Publication date: 26 August 2020

Published in: Mathematical and Numerical Approaches for Multi-Wave Inverse Problems (Search for Journal in Brave)

Abstract: In this work we consider the image reconstruction problem of sparsely sampled dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). DCE-MRI is a technique for acquiring a series of MR images before, during and after intravenous contrast agent administration, and it is used to study microvascular structure and perfusion. To overcome the ill-posedness of the related spatio-temporal inverse problem, we use regularization. In regularization one of the main problems is how to determine the regularization parameter which controls the balance between data fitting term and regularization term. Most methods for selecting this parameter require the computation of a large number of estimates even in stationary problems. In dynamic imaging, the parameter selection is even more time consuming since separate regularization parameters are needed for the spatial and temporal regularization functionals. In this work, we study the possibility of using the S-curve with DCE-MR data. We select the spatial regularization parameter using the S-curve, leaving the temporal regularization parameter as the only free parameter in the reconstruction problem. In this work, the temporal regularization parameter is selected manually by computing reconstructions with several values of the temporal regularization parameter.

Full work available at URL: https://arxiv.org/abs/2002.09129

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zbMATH Keywords

image reconstructiondynamic contrast-enhanced MRIS-curve regularizationsparsely sampled MRI

Mathematics Subject Classification ID

Signal theory (characterization, reconstruction, filtering, etc.) (94A12) Numerical methods for integral equations (65R20) Numerical methods for inverse problems for integral equations (65R32)

Cites Work

• Nonlinear total variation based noise removal algorithms
• Stable signal recovery from incomplete and inaccurate measurements
• Robust uncertainty principles: exact signal reconstruction from highly incomplete frequency information
• Total generalized variation
• Nonuniform fast fourier transforms using min-max interpolation
• Sparse tomography
• An upwind finite-difference method for total variation-based image smoothing
• Multiresolution Parameter Choice Method for Total Variation Regularized Tomography
• Sparsity-promoting Bayesian inversion

Cited In (2)

• Fast tissue classification in dynamic contrast enhanced magnetic resonance images
• Time curve analysis techniques for dynamic contrast MRI studies

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