Chemotaxis on networks: analysis and numerical approximation

DOI10.1051/M2AN/2019069zbMATH Open1445.35199arXiv1805.00925OpenAlexW3005552090MaRDI QIDQ5118614FDOQ5118614

Lukas Schöbel-Kröhn, Herbert Egger

Publication date: 26 August 2020

Published in: ESAIM: Mathematical Modelling and Numerical Analysis (Search for Journal in Brave)

Abstract: We consider the Keller-Segel model of chemotaxis on one-dimensional networks. Using a variational characterization of solutions, positivity preservation, conservation of mass, and energy estimates, we establish global existence of weak solutions and uniform bounds. This extends related results of Osaki and Yagi to the network context. We then analyze the discretization of the system by finite elements and an implicit time-stepping scheme. Mass lumping and upwinding are used to guarantee the positivity of the solutions on the discrete level. This allows us to deduce uniform bounds for the numerical approximations and to establish order optimal convergence of the discrete approximations to the continuous solution without artificial smoothness requirements. In addition, we prove convergence rates under reasonable assumptions. Some numerical tests are presented to illustrate the theoretical results.

Full work available at URL: https://arxiv.org/abs/1805.00925

Recommendations

• The scalar Keller-Segel model on networks
• Parabolic models for chemotaxis on weighted networks
• Asymptotic convergence of solutions of Keller-Segel equations in network shaped domains
• Nonnegativity of exact and numerical solutions of some chemotactic models
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zbMATH Keywords

global solutionsfinite elementsmass lumpingupwind discretization

Mathematics Subject Classification ID

Initial value problems for second-order parabolic systems (35K45) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Cell movement (chemotaxis, etc.) (92C17) PDEs on graphs and networks (ramified or polygonal spaces) (35R02)

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Cited In (5)

• Optimal Dirichlet control of partial differential equations on networks
• Chemotaxis, Reaction, Network
• Finite element approximation of a Keller-Segel model with additional self- and cross-diffusion terms and a logistic source
• Mathematical analysis of parabolic models with volume-filling effect in weighted networks
• Nonlinear flux-limited models for chemotaxis on networks

Uses Software

• Chemotaxis

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