Chemotaxis on networks: analysis and numerical approximation
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Publication:5118614
Initial value problems for second-order parabolic systems (35K45) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Cell movement (chemotaxis, etc.) (92C17) PDEs on graphs and networks (ramified or polygonal spaces) (35R02)
Abstract: We consider the Keller-Segel model of chemotaxis on one-dimensional networks. Using a variational characterization of solutions, positivity preservation, conservation of mass, and energy estimates, we establish global existence of weak solutions and uniform bounds. This extends related results of Osaki and Yagi to the network context. We then analyze the discretization of the system by finite elements and an implicit time-stepping scheme. Mass lumping and upwinding are used to guarantee the positivity of the solutions on the discrete level. This allows us to deduce uniform bounds for the numerical approximations and to establish order optimal convergence of the discrete approximations to the continuous solution without artificial smoothness requirements. In addition, we prove convergence rates under reasonable assumptions. Some numerical tests are presented to illustrate the theoretical results.
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Cited in
(8)- Optimal Dirichlet control of partial differential equations on networks
- Chemotaxis, Reaction, Network
- Finite element approximation of a Keller-Segel model with additional self- and cross-diffusion terms and a logistic source
- A hyperbolic model of chemotaxis on a network: a numerical study
- Mathematical analysis of parabolic models with volume-filling effect in weighted networks
- Nonlinear flux-limited models for chemotaxis on networks
- Parabolic models for chemotaxis on weighted networks
- Kinetic and related macroscopic models for chemotaxis on networks
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