Adaptive patient enrichment designs in therapeutic trials
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Publication:5123181
DOI10.1002/bimj.200900003zbMath1442.62681WikidataQ38355168 ScholiaQ38355168MaRDI QIDQ5123181
R. T. O'Neill, Sue-Jane Wang, H. M. James Hung
Publication date: 25 September 2020
Published in: Biometrical Journal (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1002/bimj.200900003
futility; adaptive enrichment algorithm; nested patient subset; strong control of experiment-wise type i error; weighted Z-statistic
62P10: Applications of statistics to biology and medical sciences; meta analysis