Abstract: Let be a knot in a rational homology sphere . This paper investigates the question of when modifying by adding half-twists to two oppositely-oriented strands, while keeping the rest of fixed, produces a knot isotopic to . Such a two-strand twist of order , as we define it, is a generalized crossing change when is even and a non-coherent band surgery when . A cosmetic two-strand twist on is a non-nugatory one that produces an isotopic knot. We prove that fibered knots in admit no cosmetic generalized crossing changes. Further, we show that if is fibered, then a two-strand twist of odd order that is determined by a separating arc in a fiber surface for can only be cosmetic if . After proving these theorems, we further investigate cosmetic two-strand twists of odd orders. Through two examples, we find that the second theorem above becomes false if `separating' is removed, and that a key technical proposition fails when the order equals 1. A closer look at an order-one example, an instance of cosmetic band surgery on the unknot, reveals it to be nearly trivial in a sense that we name `weakly nugatory'. We correct the technical proposition to obtain a means of using double branched covers to show that certain band surgeries are weakly nugatory. As an application, we prove that every cosmetic band surgery on the unknot is of this type.
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