A generalization of Kingman's model of selection and mutation and the Lenski experiment

DOI10.1016/J.MBS.2016.12.007MaRDI QIDQ512673zbMATHOpenAlexWikidataFDO

Authors Linglong Yuan

Publication date 27 February 2017

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1506.02298

zbMATH Keywords

Lenski experimentfitness functionEscherichia colihouse of cardsselection-mutation balancetype distribution

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Abstract: Kingman's model of selection and mutation studies the limit type value distribution in an asexual population of discrete generations and infinite size undergoing selection and mutation. This paper generalizes the model to analyse the long-term evolution of Escherichia. coli in Lenski experiment. Weak assumptions for fitness functions are proposed and the mutation mechanism is the same as in Kingman's model. General macroscopic epistasis are designable through fitness functions. Convergence to the unique limit type distribution is obtained.

Recommendations

• Modelling and simulating Lenski's long-term evolution experiment
• Kingman's model with random mutation probabilities: convergence and condensation. I
• An individual-based model for the Lenski experiment, and the deceleration of the relative fitness
• Kingman's model with random mutation probabilities: convergence and condensation. II
• The selection mutation equation

Cites work

• scientific article; zbMATH DE number 3274494 (Why is no real title available?)
• A generalized model of mutation-selection balance with applications to aging
• A simple model for the balance between selection and mutation
• A stochastic model concerning the maintenance of genetic variability in quantitative characters.
• An individual-based model for the Lenski experiment, and the deceleration of the relative fitness
• Emergence of condensation in Kingman's model of selection and mutation
• From Individual Stochastic Processes to Macroscopic Models in Adaptive Evolution
• Global stability of genetic systems governed by mutation and selection
• Global stability of genetic systems governed by mutation and selection. II
• Mutation-selection balance and continuum-of-alleles models
• On the properties of bilinear models for the balance between genetic mutation and selection
• Unifying evolutionary dynamics: from individual stochastic processes to macroscopic models

Cited in

(10)

• Kingman's model with random mutation probabilities: convergence and condensation. I
• An individual-based model for the Lenski experiment, and the deceleration of the relative fitness
• Emergence of condensation in Kingman's model of selection and mutation
• Study the genetic variation using eta functions
• The shape of the emerging condensate in effective models of condensation
• Branching with selection and mutation. I: Mutant fitness of Fréchet type
• Kingman's model with random mutation probabilities: convergence and condensation. II
• Modelling and simulating Lenski's long-term evolution experiment
• Steady states in a non-conserving zero-range process with extensive rates as a model for the balance of selection and mutation
• Lotka-Volterra model with mutations and generative adversarial networks

This page was built for publication: A generalization of Kingman's model of selection and mutation and the Lenski experiment

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q512673)