A generalization of Kingman's model of selection and mutation and the Lenski experiment
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Publication:512673
DOI10.1016/J.MBS.2016.12.007zbMATH Open1361.92049arXiv1506.02298OpenAlexW2523738447WikidataQ48030110 ScholiaQ48030110MaRDI QIDQ512673FDOQ512673
Authors: Linglong Yuan 
Publication date: 27 February 2017
Published in: Mathematical Biosciences (Search for Journal in Brave)
Abstract: Kingman's model of selection and mutation studies the limit type value distribution in an asexual population of discrete generations and infinite size undergoing selection and mutation. This paper generalizes the model to analyse the long-term evolution of Escherichia. coli in Lenski experiment. Weak assumptions for fitness functions are proposed and the mutation mechanism is the same as in Kingman's model. General macroscopic epistasis are designable through fitness functions. Convergence to the unique limit type distribution is obtained.
Full work available at URL: https://arxiv.org/abs/1506.02298
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Cited In (8)
- An individual-based model for the Lenski experiment, and the deceleration of the relative fitness
- Branching with selection and mutation. I: Mutant fitness of Fréchet type
- The shape of the emerging condensate in effective models of condensation
- Kingman's model with random mutation probabilities: convergence and condensation. II
- Emergence of condensation in Kingman's model of selection and mutation
- Study the genetic variation using eta functions
- Kingman’s model with random mutation probabilities: convergence and condensation I
- Steady states in a non-conserving zero-range process with extensive rates as a model for the balance of selection and mutation
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