On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons

MaRDI QIDQ5134889zbMATH OpenFDO

Authors Addolorata Marasco, Alessandro Limongiello, Cristina Marchetti, Helene Marie, Brunello Tirozzi, Michele Migliore, Daniela Bianchi

Publication date 17 November 2020

zbMATH Keywords

bifurcation analysisCA1 pyramidal neurondepolarization blockkinetics

Mathematics Subject Classification ID

Neural biology (92C20)

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Cites work

• Control of firing patterns by two transient potassium currents: leading spike, latency, bistability
• Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons
• Practical bifurcation and stability analysis
• Role of an \(A\)-type \(K^+\) conductance in the back-propagating of action potentials in the dendrites of hippocampal pyramidal neurons
• Scientific computing with Mathematica. Mathematical problems for ordinary differential equations. Incl. 1 CD-ROM
• The bifurcation of periodic solutions in the Hodgkin-Huxley equations

Cited in

(8)

• Intermittency in the Hodgkin-Huxley model
• The domain of neuronal firing on a plane of input current and conductance
• Automata complete computation with Hodgkin-Huxley neural networks composed of synfire rings
• A model of on/off transitions in neurons of the deep cerebellar nuclei: deciphering the underlying ionic mechanisms
• Interneuronal dynamics facilitate the initiation of spike block in cortical microcircuits
• An adaptive generalized leaky integrate-and-fire model for hippocampal CA1 pyramidal neurons and interneurons
• Single-compartment model of a pyramidal neuron, fitted to recordings with current and conductance injection
• Kinetic modeling approach for a heterogeneous neuronal network activity using adjacency matrices

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