A nonlinear mixed-effects model for multivariate longitudinal data with partially observed outcomes with application to HIV disease dynamics

DOI10.1080/02664763.2016.1177494MaRDI QIDQ5138548zbMATH OpenOpenAlexFDO

Authors Artz G. Luwanda, H. Mwambi

Publication date 4 December 2020

Published in Journal of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/02664763.2016.1177494

zbMATH Keywords

incomplete datamultivariate responseleft-censored dataHIV dynamical systempartial marker dropoutstochastic approximation expectation-maximisation algorithm

Mathematics Subject Classification ID

General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Estimation in multivariate analysis (62H12)

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Cites work

• A Random-Effects Model for Multiple Characteristics With Possibly Missing Data
• An EM Algorithm for Nonlinear Random Effects Models
• An EM algorithm for the estimation of parametric and nonparametric hierarchical nonlinear models
• Convergence of a stochastic approximation version of the EM algorithm
• Maximum Likelihood Estimation in Dynamical Models of HIV
• Maximum Likelihood Estimation of Long-Term HIV Dynamic Models and Antiviral Response
• Missing data methods in longitudinal studies: a review
• Multivariate Repeated-Measurement or Growth Curve Models with Multivariate Random-Effects Covariance Structure
• Practical identifiability of HIV dynamics models
• REML estimation of variance parameters in nonlinear mixed effects models using the SAEM algorithm
• Random-Effects Models for Longitudinal Data
• Simultaneous Inference for Semiparametric Nonlinear Mixed‐Effects Models with Covariate Measurement Errors and Missing Responses
• Statistical methods for HIV dynamic studies in AIDS clinical trials

Cited in

(6)

• Predictive cross-validation for the choice of linear mixed-effects models with application to data from the swiss HIV cohort study
• A two-stage estimation method for random coefficient differential equation models with application to longitudinal HIV dynamic data
• A semiparametric nonlinear mixed-effects model with non-ignorable missing data and measurement errors for HIV viral data
• Bivariate Modelling of Longitudinal Measurements of Two Human Immunodeficiency Type 1 Disease Progression Markers in the Presence of Informative Drop-Outs
• A nonlinear mixed-effects model for multivariate longitudinal data with dropout with application to HIV disease dynamics
• Joint penalized spline modeling of multivariate longitudinal data, with application to HIV‐1 RNA load levels and CD4 cell counts

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