Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling

DOI10.1093/IMAMMB/DQAB005zbMATH Open1473.92012arXiv2104.07165OpenAlexW3111978766WikidataQ113819102 ScholiaQ113819102MaRDI QIDQ5157576FDOQ5157576

Authors: Peter Mortensen, Hao Gao, Radostin D. Simitev 

Publication date: 19 October 2021

Published in: Mathematical Medicine and Biology: A Journal of the IMA (Search for Journal in Brave)

Abstract: The analytical theory of our earlier study (Mortensen et al. (2021), Mathematical Medicine and Biology, 38(1), pp. 106-131) is extended to address the outstanding cases of fibroblast barrier distribution and myocyte strait distribution. In particular, closed-form approximations to the resting membrane potential and to the critical parameter values for propagation are derived for these two non-uniform fibroblast distributions and are in good agreement with numerical estimates.

Full work available at URL: https://arxiv.org/abs/2104.07165

Recommendations

• Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling
• A bidomain model of human cardiac tissue incorporating a capillary microstructure
• Existence of excitation waves for a collection of cardiomyocytes electrically coupled to fibroblasts
• A simple analytical model of action potential duration profile in electrotonically-coupled cells
• MODELING EXCITATION AND PROPAGATION OF ACTION POTENTIALS ACROSS INHOMOGENEOUS VENTRICULAR TISSUE

zbMATH Keywords

asymptotic approximationelectrophysiologyrefractorinessmyocyte-fibroblast coupling

Mathematics Subject Classification ID

Physiology (general) (92C30)

Cited In (3)

• Simulations of passive properties and action potential conduction in an idealized bullfrog atrial trabeculum
• Excitation-contraction coupling between human atrial myocytes with fibroblasts and stretch activated channel current: a simulation study
• Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling

This page was built for publication: Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5157576)