Global and local stability for a non-linear hyperbolic system model for the role of stem cells in physiological homeostasis

DOI10.1007/S40314-014-0213-0zbMATH Open1362.35178arXiv1408.5070OpenAlexW2032048303MaRDI QIDQ520252FDOQ520252

Laura Di Bernardo, Donatella Donatelli

Publication date: 3 April 2017

Published in: Computational and Applied Mathematics (Search for Journal in Brave)

Abstract: In this paper we propose an existence and uniqueness theory for the solutions of a system of non-linear hyperbolic conservation laws, structured in age and maturity variables, representing a tissue environment. In particular we are interested in the investigation of the role of stem cells in its homeostasis. The main result presented in this paper is the consistence of the stability results arising from the analisys of the model we designed with the experimental observations on which several branches of medicine are currently attempting to trade on their research activity.

Full work available at URL: https://arxiv.org/abs/1408.5070

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zbMATH Keywords

age-dependentGompertzian growth

Mathematics Subject Classification ID

Medical applications (general) (92C50) Stability in context of PDEs (35B35) First-order nonlinear hyperbolic equations (35L60) Hyperbolic conservation laws (35L65) Initial-boundary value problems for second-order hyperbolic systems (35L53)

Cites Work

• Non-linear age-dependent population dynamics
• Title not available (Why is that?)
• Title not available (Why is that?)
• Global stability of a partial differential equation with distributed delay due to cellular replication
• Optimal Harvesting for Periodic Age-Dependent Population Dynamics
• Global stability in a delayed partial differential equation describing cellular replication
• A new criterion for the global stability of simultaneous cell replication and maturation processes
• Some considerations on the mathematical approach to nonlinear age dependent population dynamics
• On the global stability of the logistic age-dependent population growth
• Asymptotic behavior of a singular transport equation modelling cell division

Cited In (3)

• Stability of control networks in autonomous homeostatic regulation of stem cell lineages
• Stability and Hopf bifurcation in a mathematical model of pluripotent stem cell dynamics
• Principal spectral theory for nonlocal systems and applications to stem cell regeneration models

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