Semiparametric regression using variational approximations

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Publication:5208080

DOI10.1080/01621459.2018.1518235zbMATH Open1428.62156arXiv1810.01949OpenAlexW3104810320WikidataQ129280276 ScholiaQ129280276MaRDI QIDQ5208080FDOQ5208080


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Publication date: 15 January 2020

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Abstract: Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional components in conjunction with a quadratic penalty to control for overfitting. Estimation and inference are then generally performed based on the penalized likelihood, or under a mixed model framework. The penalized likelihood framework is fast but potentially unstable, and choosing the smoothing parameters needs to be done externally using cross-validation, for instance. The mixed model framework tends to be more stable and offers a natural way for choosing the smoothing parameters, but for non-normal responses involves an intractable integral. In this article, we introduce a new framework for semiparametric regression based on variational approximations. The approach possesses the stability and natural inference tools of the mixed model framework, while achieving computation times comparable to using penalized likelihood. Focusing on generalized additive models, we derive fully tractable variational likelihoods for some common response types. We present several features of the variational approximation framework for inference, including a variational information matrix for inference on parametric components, and a closed-form update for estimating the smoothing parameter. We demonstrate the consistency of the variational approximation estimates, and an asymptotic normality result for the parametric component of the model. Simulation studies show the variational approximation framework performs similarly to and sometimes better than currently available software for fitting generalized additive models.


Full work available at URL: https://arxiv.org/abs/1810.01949




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