Marginal screening of 2 2 tables in large-scale case-control studies

DOI10.1111/BIOM.12957MaRDI QIDQ5214459zbMATH OpenOpenAlexWikidataFDO

Authors Ian W. Mckeague, Min Qian

Publication date 7 February 2020

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/biom.12957

zbMATH Keywords

family-wise error rategenome-wide association studiesmultiple testingpost-selection inference

Mathematics Subject Classification ID

Paired and multiple comparisons; multiple testing (62J15) Statistical block designs (62K10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Epidemiology (92D30)

Recommendations

• On the screening of large numbers of significance tests
• A multiple testing approach to high-dimensional association studies with an application to the detection of associations between risk factors of heart disease and genetic polymorphisms
• Efficient p-value estimation in massively parallel testing problems
• Powerful test based on conditional effects for genome-wide screening
• How to analyze many contingency tables simultaneously in genetic association studies

Cited in

(1)

• Joint consideration of multiple loci and their influence on a disease in case-control studies

This page was built for publication: Marginal screening of \(2 \times 2\) tables in large-scale case-control studies

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5214459)