Composite kernel machine regression based on likelihood ratio test for joint testing of genetic and gene–environment interaction effect

DOI10.1111/BIOM.13003zbMATH Open1436.62662OpenAlexW2901615848WikidataQ93086783 ScholiaQ93086783MaRDI QIDQ5214523FDOQ5214523

Authors:

Publication date: 7 February 2020

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/biom.13003

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zbMATH Keywords

likelihood ratio testspectral decompositiongene-environment interactionsmultiple variance componentskernel machine testingunidentifiable conditions

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of statistics to environmental and related topics (62P12) Inference from stochastic processes and spectral analysis (62M15) Ecology (92D40)

Cited In (5)

• A unified set-based test with adaptive filtering for gene-environment interaction analyses
• Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines
• Modeling and testing for joint association using a genetic random field model
• Kernel Machine Approach to Testing the Significance of Multiple Genetic Markers for Risk Prediction
• VCSEL: prioritizing SNP-set by penalized variance component selection

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