Composite kernel machine regression based on likelihood ratio test for joint testing of genetic and gene–environment interaction effect

DOI10.1111/BIOM.13003MaRDI QIDQ5214523zbMATH OpenOpenAlexWikidataFDO

Authors

Publication date 7 February 2020

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/biom.13003

zbMATH Keywords

likelihood ratio testspectral decompositiongene-environment interactionsmultiple variance componentskernel machine testingunidentifiable conditions

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of statistics to environmental and related topics (62P12) Inference from stochastic processes and spectral analysis (62M15) Ecology (92D40)

Recommendations

• Kernel Machine Approach to Testing the Significance of Multiple Genetic Markers for Risk Prediction
• Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines
• Joint test of parametric and nonparametric effects in partial linear models for gene-environment interaction
• A unified set-based test with adaptive filtering for gene-environment interaction analyses
• A Scalable Hierarchical Lasso for Gene–Environment Interactions
• Gene–environment interaction identification via penalized robust divergence
• Semiparametric Regression of Multidimensional Genetic Pathway Data: Least‐Squares Kernel Machines and Linear Mixed Models
• Equivalence of kernel machine regression and kernel distance covariance for multidimensional phenotype association studies
• Modeling and testing for joint association using a genetic random field model
• Semiparametric nonlinear regression for detecting gene and environment interactions

Cited in

(5)

• Kernel Machine Approach to Testing the Significance of Multiple Genetic Markers for Risk Prediction
• Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines
• Modeling and testing for joint association using a genetic random field model
• A unified set-based test with adaptive filtering for gene-environment interaction analyses
• VCSEL: prioritizing SNP-set by penalized variance component selection

This page was built for publication: Composite kernel machine regression based on likelihood ratio test for joint testing of genetic and gene–environment interaction effect

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5214523)