Actin Automata: Phenomenology and Localizations

DOI10.1142/S0218127415500303MaRDI QIDQ5246700zbMATH OpenFDO

Authors Andrew Adamatzky, Richard Mayne

Publication date 22 April 2015

Published in International Journal of Bifurcation and Chaos in Applied Sciences and Engineering (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1408.3676

zbMATH Keywords

actinautomatalocalizations

Mathematics Subject Classification ID

Cellular automata (computational aspects) (68Q80)

Abstract: Actin is a globular protein which forms long filaments in the eukaryotic cytoskeleton, whose roles in cell function include structural support, contractile activity to intracellular signalling. We model actin filaments as two chains of one-dimensional binary-state semi-totalistic automaton arrays to describe hypothetical signalling events therein. Each node of the actin automaton takes state `0' (resting) or `1' (excited) and updates its state in discrete time depending on its neighbour's states. We analyse the complete rule space of actin automata using integral characteristics of space-time configurations generated by these rules and compute state transition rules that support travelling and mobile localizations. Approaches towards selection of the localisation supporting rules using the global characteristics are outlined. We find that some properties of actin automata rules may be predicted using Shannon entropy, activity and incoherence of excitation between the polymer chains. We also show that it is possible to infer whether a given rule supports travelling or stationary localizations by looking at ratios of excited neighbours are essential for generations of the localizations. We conclude by applying biomolecular hypotheses to this model and discuss the significance of our findings in context with cell signalling and emergent behaviour in cellular computation.

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Cites work

• Collision-based computing in biopolymers and their automata models
• Collision-based implementation of a two-bit adder in excitable cellular automaton

Cited in

(12)

• On the complexity of asynchronous freezing cellular automata
• Random expansion method for the generation of complex cellular automata
• Brain and its universal logical model of multi-agent biological systems
• Actin automata with memory
• Logical Gates Implemented by Solitons at the Junctions Between One-Dimensional Lattices
• scientific article; zbMATH DE number 3887492 (Why is no real title available?)
• PhyChip: Growing Computers with Slime Mould
• scientific article; zbMATH DE number 1120696 (Why is no real title available?)
• Fungal automata
• Logical gates via gliders collisions
• On binary-state phyllosilicate automata
• Cellular automata modelling of slime mould actin network signalling

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