L-infinity optimization to linear spaces and phylogenetic trees

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Publication:5346563




Abstract: Given a distance matrix consisting of pairwise distances between species, a distance-based phylogenetic reconstruction method returns a tree metric or equidistant tree metric (ultrametric) that best fits the data. We investigate distance-based phylogenetic reconstruction using the linfty-metric. In particular, we analyze the set of linfty-closest ultrametrics and tree metrics to an arbitrary dissimilarity map to determine its dimension and the tree topologies it represents. In the case of ultrametrics, we decompose the space of dissimilarity maps on 3 elements and on 4 elements relative to the tree topologies represented. Our approach is to first address uniqueness issues arising in linfty-optimization to linear spaces. We show that the linfty-closest point in a linear space is unique if and only if the underlying matroid of the linear space is uniform. We also give a polyhedral decomposition of rm based on the dimension of the set of linfty-closest points in a linear space.





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