Joint statistics of strongly correlated neurons via dimensionality reduction

DOI10.1088/1751-8121/AA677EzbMATH Open1377.82035arXiv1609.00900OpenAlexW2512474434MaRDI QIDQ5347989FDOQ5347989

Authors: Taşkın Deniz, Stefan Rotter 

Publication date: 11 August 2017

Published in: Journal of Physics A: Mathematical and Theoretical (Search for Journal in Brave)

Abstract: The relative timing of action potentials in neurons recorded from local cortical networks often shows a non-trivial dependence, which is then quantified by cross-correlation functions. Theoretical models emphasize that such spike train correlations are an inevitable consequence of two neurons being part of the same network and sharing some synaptic input. For non-linear neuron models, however, explicit correlation functions are difficult to compute analytically, and perturbative methods work only for weak shared input. In order to treat strong correlations, we suggest here an alternative non-perturbative method. Specifically, we study the case of two leaky integrate-and-fire neurons with strong shared input. Correlation functions derived from simulated spike trains fit our theoretical predictions very accurately. Using our method, we computed the non-linear correlation transfer as well as correlation functions that are asymmetric due to inhomogeneous intrinsic parameters or unequal input.

Full work available at URL: https://arxiv.org/abs/1609.00900

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zbMATH Keywords

singular value decompositionMarkov processcorrelated jump equationsstrongly correlated neural dynamics

Mathematics Subject Classification ID

Eigenvalues, singular values, and eigenvectors (15A18) Stochastic methods (Fokker-Planck, Langevin, etc.) applied to problems in time-dependent statistical mechanics (82C31) Neural nets applied to problems in time-dependent statistical mechanics (82C32)

Cites Work

• Can Spike Coordination Be Differentiated from Rate Covariation?
• Mathematical Analysis of Random Noise
• Shifting spike times or adding and deleting spikes -- how different types of noise shape signal transmission in neural populations
• Higher-Order Statistics of Input Ensembles and the Response of Simple Model Neurons
• Spiking Neuron Models
• Population density models of integrate-and-fire neurons with jumps: well-posedness
• Phenomenological models of synaptic plasticity based on spike timing
• Statistical structure of neural spiking under non-Poissonian or other non-white stimulation
• The Many Proofs and Applications of Perron's Theorem
• Finite volume and asymptotic methods for stochastic neuron models with correlated inputs
• Impact of correlated inputs to neurons: modeling observations from \textit{in vivo} intracellular recordings

Cited In (2)

• Cross-intensity functions and the estimate of spike-time jitter
• Information theoretic analysis of action potential trains. I: Analysis of correlation between two neurons

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