Heterogeneous treatment effects in stratified clinical trials with time‐to‐event endpoints

DOI10.1002/bimj.201600047zbMath1422.62318OpenAlexW2593923038WikidataQ38927246 ScholiaQ38927246MaRDI QIDQ5348691

Axel Benner, Annette Kopp-Schneider, Christina Beisel, Christina Kunz

Publication date: 18 August 2017

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201600047

zbMATH Keywords

sample sizeCox proportional hazards modelbiomarkerslog-rank testshared frailty modeltrial design

Mathematics Subject Classification ID

Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Reliability and life testing (62N05)

Related Items (1)

Sample size estimation for cancer randomized trials in the presence of heterogeneous populations

Cites Work

• Unnamed Item
• The asymptotic theory of permutation statistics.
• The frailty model.
• Sample-Size Formula for the Proportional-Hazards Regression Model
• Evaluation of Sample Size and Power for Analyses of Survival with Allowance for Nonuniform Patient Entry, Losses to Follow-Up, Noncompliance, and Stratification

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