Stability of stationary solutions of piecewise affine differential equations describing gene regulatory networks

DOI10.1016/J.JMAA.2011.02.034MaRDI QIDQ536277zbMATH OpenOpenAlexFDO

Authors A. Machina, Arcady Ponosov

Publication date 16 May 2011

Published in Journal of Mathematical Analysis and Applications (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jmaa.2011.02.034

zbMATH Keywords

Filippov solutionstability analysisdifferential inclusiongene regulatory networksingular stationary point

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Ordinary differential inclusions (34A60) Transformation and reduction of ordinary differential equations and systems, normal forms (34C20) Stability of solutions to ordinary differential equations (34D20)

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• scientific article; zbMATH DE number 5561850

Cites work

• A class of piecewise linear differential equations arising in biological models
• A methodological basis for description and analysis of systems with complex switch-like interactions
• Analysis and generic properties of gene regulatory networks with graded response functions
• Chaos, fractals, and noise: Stochastic aspects of dynamics.
• Differential equations with discontinuous right-hand sides, and differential inclusions
• Filippov solutions in the analysis of piecewise linear models describing gene regulatory networks
• Global analysis of steady points for systems of differential equations with sigmoid interactions
• Logical identification of all steady states: The concept of feedback loop characteristic states
• Piecewise-linear models of genetic regulatory networks: equilibria and their stability

Cited in

(10)

• Sensitive dependence on initial conditions in gene networks
• Periodic solutions of gene networks with steep sigmoidal regulatory functions
• Filippov solutions in the analysis of piecewise linear models describing gene regulatory networks
• Piecewise-linear models of genetic regulatory networks: equilibria and their stability
• Numerical simulation of piecewise-linear models of gene regulatory networks using complementarity systems
• Dynamical systems coupled with monotone set-valued operators: formalisms, applications, well-posedness, and stability
• Differential inclusions and Filippov solutions in the analysis of piecewise linear models describing gene regulatory networks
• State transition graph and stability of singular equilibria for piecewise linear biological models
• On inclusions arising in neural field modeling
• Coarse-grained optimization-driven design and piecewise linear modeling of synthetic genetic circuits

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