Optimal Screening and Discovery of Sparse Signals with Applications to Multistage High Throughput Studies

DOI10.1111/rssb.12171zbMath1414.62042MaRDI QIDQ5378161

T. Tony Cai, Wenguang Sun

Publication date: 12 June 2019

Published in: Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/rssb.12171

zbMATH Keywords

phase transition; data screening; false discovery rate; high throughput screening; false negative rate; discovery boundary; multistage adaptive testing; screening boundary

Mathematics Subject Classification ID

62G10: Nonparametric hypothesis testing

94A12: Signal theory (characterization, reconstruction, filtering, etc.)

94A13: Detection theory in information and communication theory

62L10: Sequential statistical analysis

62J15: Paired and multiple comparisons; multiple testing

62C25: Compound decision problems in statistical decision theory