Optimal screening and discovery of sparse signals with applications to multistage high throughput studies

DOI10.1111/RSSB.12171MaRDI QIDQ5378161zbMATHOpenAlexFDO

Authors Wenguang Sun, T. Tony Cai

Publication date 12 June 2019

Published in Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/rssb.12171

zbMATH Keywords

false discovery ratephase transitionhigh throughput screeningfalse negative ratedata screeningdiscovery boundarymultistage adaptive testingscreening boundary

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Sequential statistical analysis (62L10) Signal theory (characterization, reconstruction, filtering, etc.) (94A12) Paired and multiple comparisons; multiple testing (62J15) Detection theory in information and communication theory (94A13) Compound decision problems in statistical decision theory (62C25)

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(10)

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• Optimal Transitions for Targeted Protein Quantification: Best Conditioned Submatrix Selection
• Efficient signal inclusion with genomic applications
• Feature screening in large scale cluster analysis
• Search for sparse active inputs: a review
• False discovery rate control for lesion-symptom mapping with heterogeneous data via weighted \(p\)-values
• Estimating the proportion of signal variables under arbitrary covariance dependence
• Hierarchical recognition of sparse patterns in large-scale simultaneous inference
• Adaptive sparse estimation with side information
• Directional false discovery rate control in large-scale multiple comparisons

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