A Geometric Approach to Comparing Treatments for Rapidly Fatal Diseases

DOI10.1111/j.1541-0420.2005.00434.xzbMath1091.62126OpenAlexW1966552463WikidataQ51945676 ScholiaQ51945676MaRDI QIDQ5473225

Peter F. Thall, Leiko H. Wooten, Elizabeth J. Shpall

Publication date: 20 June 2006

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2005.00434.x

zbMATH Keywords

simulationclinical trialscompeting risksadaptive designBayesian designcord blood transplantation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15)

Related Items (3)

Monitoring phase II comparative clinical trials with two endpoints and penalty for adverse events ⋮ Patient‐Specific Dose Finding Based on Bivariate Outcomes and Covariates ⋮ Some geometric methods for constructing decision criteria based on two-dimensional parame\-ters

Cites Work

• Double exponential formulas for numerical integration
• Design and Analysis of Group Sequential Clinical Trials with Multiple Primary Endpoints
• Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints
• Designs for Phase II Trials Allowing for a Trade-Off between Response and Toxicity
• Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials
• Selecting Therapeutic Strategies Based on Efficacy and Death in Multicourse Clinical Trials
• Safe and Effective Importance Sampling
• Treatment Comparisons Based on Two‐Dimensional Safety and Efficacy Alternatives in Oncology Trials
• Approximate Bayesian Evaluation of Multiple Treatment Effects
• A Simplex Method for Function Minimization

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