Computational Methods and Results for Structured Multiscale Models of Tumor Invasion
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Abstract: We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss the scientific-computing methodology used to solve the model equations. The models and methodology presented in this paper form the basis for developing and treating increasingly complex, mechanistic models of tumor invasion that will be more predictive and less phenomenological. Because many of the features of the cancer models, such as taxis, aging and growth, are seen in other biological systems, the models and methods discussed here also provide a template for handling a broader range of biological problems.
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- scientific article; zbMATH DE number 6995507 (Why is no real title available?)
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- A multiscale moving boundary model arising in cancer invasion
- scientific article; zbMATH DE number 2205563 (Why is no real title available?)
- MATHEMATICAL ANALYSIS AND CHALLENGES ARISING FROM MODELS OF TUMOR GROWTH
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- Modeling and analysis of a multilayer solid tumour with cell physiological age and resource limitations
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- Phenotype structuring in collective cell migration: a tutorial of mathematical models and methods
- The work of Glenn F. Webb
- A second-order positivity preserving central-upwind scheme for chemotaxis and haptotaxis models
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