Protein homology detection through alignment of Markov random fields. Using MRFalign

DOI10.1007/978-3-319-14914-1MaRDI QIDQ5497110zbMATH OpenOpenAlexFDO

Authors Jinbo Xu, Sheng Wang, Jianzhu Ma

Publication date 3 February 2015

Published in SpringerBriefs in Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-319-14914-1

zbMATH Keywords

hidden Markov modelMarkov random fieldsposition-specific scoring matrixprotein homology

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Protein sequences, DNA sequences (92D20) Research exposition (monographs, survey articles) pertaining to biology (92-02)

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(8)

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• Integrating subcellular location for improving machine learning models of remote homology detection in eukaryotic organisms
• Research in Computational Molecular Biology
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• Bayesian matching of unlabeled marked point sets using random fields, with an application to molecular alignment
• Probing the protein space for extending the detection of weak homology folds

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