Statistical Inference in Evolutionary Models of DNA Sequences via the EM Algorithm

DOI10.2202/1544-6115.1127zbMATH Open1081.62094OpenAlexW2257584626WikidataQ51942767 ScholiaQ51942767MaRDI QIDQ5700522FDOQ5700522

Jens Ledet Jensen, Asger Hobolth

Publication date: 28 October 2005

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: http://www.bepress.com/sagmb/vol4/iss1/art18

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Mathematics Subject Classification ID

Markov processes: estimation; hidden Markov models (62M05) Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15) Protein sequences, DNA sequences (92D20)

Cited In (14)

• Maximum likelihood estimation and natural pairwise estimating equations are identical for three sequences and a symmetric 2-state substitution model
• Maximum likelihood estimation of symmetric group-based models via numerical algebraic geometry
• Computational methods for birth-death processes
• The multivariate Wright-Fisher process with mutation: moment-based analysis and inference using a hierarchical beta model
• Summary Statistics for Endpoint-Conditioned Continuous-Time Markov Chains
• Statistical inference for DNA sequences of promoters: a non-stationary qualitative model
• The jigsaw puzzle of sequence phenotype inference: piecing together Shannon entropy, importance sampling, and empirical Bayes
• Simulation from endpoint-conditioned, continuous-time Markov chains on a finite state space, with applications to molecular evolution
• ML, PL, QL in Markov Chain Models
• Generator estimation of Markov jump processes
• Counting labeled transitions in continuous-time Markov models of evolution
• Consistent estimation for discretely observed Markov jump processes with an absorbing state
• Title not available (Why is that?)
• Mixed Model Analysis of DNA Sequence Evolution

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