Genomic control for association studies: a semiparametric test to detect excess-haplotype sharing

DOI10.1093/BIOSTATISTICS/1.4.369zbMATH Open1089.62527OpenAlexW2114184409WikidataQ73838425 ScholiaQ73838425MaRDI QIDQ5701092FDOQ5701092

Bernie Devlin, Larry Wasserman, Kathryn Roeder

Publication date: 2 November 2005

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/1.4.369

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zbMATH Keywords

Score testLinkage disequilibriumMixture modelsKernel density estimateHaplotypes

Mathematics Subject Classification ID

Density estimation (62G07) Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Cited In (4)

• Modified likelihood ratio test for homogeneity in a mixture of von Mises distributions
• A cross-population extended haplotype-based homozygosity score test to detect positive selection in genome-wide scans
• Genomic control, a new approach to genetic-based association studies.
• Hypothesis Testing in a Mixture Case-Control Model

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